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ST. LUKE'S HOSPITAL • COLUMBUS, NC • (828) 894-3311

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St. Luke's Cancer & Infusion Center


Dr. Joe Stephenson, a nationally recognized oncologist and hematologist, is the Director of the St. Luke's Cancer & Infusion Center. His leadership is a game-changer for cancer patients throughout the region.

56 Hospital Drive, Building 4 • Columbus, NC 28722
Office: 828-894-0111 • Fax: 828-894-0746
Infusion Desk: 828-894-0638 • Clinic Desk: 828-894-0112
Monday thru Thursday from 8:00 a.m. to 5:00 p.m.

Joe Stephenson, MD

Savannah Hightower, AGAC-NP


At St. Luke's Cancer & Infusion Center, we've strongly embraced preventative strategies, molecular profiling through genetic, genomic, and germline testing, and the promise offered through immunotherapy. St. Luke's is at the forefront of pathology, diagnostics, and therapeutics and is on par with the most renowned institutions in America. St. Luke's Cancer and Infusion Center is advancing cancer care in Polk County and the surrounding region.

From the moment you walk in our front door, you are family. And the therapies that you receive are personalized to address the considerable variants in each patient's environment, genetics, and habits to deliver individualized precision medicine.

Dr. Joe Stephenson, our medical oncologist is one of the most highly skilled physicians in the country and is at the vanguard of diagnostics, treatment, and research options. Every day, we learn more about how and when to manipulate the human immune system. The key is the timing of therapy and knowing when to re-engage the body's immune system. To create profile panels, we test nearly every St. Luke's Cancer & Infusion Center patient for molecular drivers. The importance of molecular diagnostics is the roadmap for treatment it provides. And molecular diagnostics dictate how aggressively we treat.

St. Luke's Cancer & Infusion: Treating the mind, body, and soul.


Molecular Profiling on malignant specimens
The Promise of Immunotherapy


PREVENTATIVE PROGRAMS at St. Luke's, have moved to the frontline in the battle against cancer. Preventing cancer is a surefire way to survive it. St. Luke's Cancer & Infusion Center has created a one-stop cancer prevention and early detection clinic. High-risk cancer screenings are an essential component of preventive medicine. We recommend these screenings for individuals who are at an elevated risk of developing certain types of cancer due to factors such as family history, genetic mutations, or previous exposure to carcinogens. The goal of high-risk cancer screenings is to detect cancer at an early stage when it is more treatable, which can ultimately lead to better outcomes.

Prevention clinics at St. Luke's include:

Lung Cancer Screening is a low-dose CT scan of your chest to find cancer before symptoms appear. The screening at St. Luke's provides much greater detail and is most helpful in guiding treatment for those at moderate risk of developing lung cancer.

High-Risk Breast Cancer Prevention Clinic is for women with a Gail Score above 1.7%. Convincing evidence for some preventative treatments offered through the clinic can result in a risk reduction of developing breast cancer by as much as fifty percent.

Contrast Enhanced Mammography creates comprehensive diagnostic studies that reveal, with unparalleled sensitivity, exceptional clinical detail with contrast-enhanced mammography (CEM). Especially beneficial for women with dense breasts, our latest software suite creates comprehensive diagnostic studies with significantly more detail.

The Colonoscopy is one of the most effective means of screening for cancer and preventing a tumor from developing.

3D Mammography detects up to 65% more invasive breast cancers than 2D mammography. And it reduces false positives by as much as 40% It is the only mammogram that is FDA approved as "superior" for dense breast tissue.

World-class Computed Tomography


Additional Treatments

St. Luke's Cancer & Infusion Center is available to provide appointments and treatments Monday thru Thursday from 8:00 a.m. to 5:00 p.m.

Cancer & Infusion Center Referral Form